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| 1 | 一种形态类似于黏液性平滑肌肉瘤的新型高级别子宫内膜间质肉瘤显示文摘子宫内膜间质肉瘤占子宫恶性肿瘤的1%,占子宫恶性间叶肿瘤的15%。WHO(2014)生殖肿瘤分类将子宫内膜间质肉瘤分为低级别子宫内膜间质肉瘤、高级别子宫内膜间质肉瘤及未分化子宫肉瘤。子宫内膜间质肉瘤常因频发染色体易位,致使发生参与表观遗传调控相关的基因融合。迄今为止,仅发现YWHAE-NUTM2重排与明确的高级别形态学及侵袭性临床行为密切相关。 | Hoang L N Aneja A Niamh C 黄爱清 余英豪 | 2017 | 临床与实验病理学杂志2017，33，7： | 9 |
| 2 | CYLD mediates ciliogenesis in multiple organs by deubiquitinating Cep70 and inactivating HDAC6显示文摘睫是毛一般的细胞器从房间表面延长与重要感觉并且活动性功能。睫的缺点能导致作为 ciliopathies 知道的大量人的疾病。然而,控制 ciliogenesis 的分子的机制仍然保持糟糕定义。这里,我们显示出那 cylindromatosis (CYLD ) ,怀有 deubiquitinase 活动的肿瘤 suppressor 蛋白质,在多重机关在主要、能动的睫的集会起一个关键作用。CYLD 猛烈老鼠 polydactyly 展出并且各种各样的睫的缺点,例如在基础身体抛锚和基础身体和 axenomes 的组织的破坏的失败。CYLD 的睫的功能部分从 70 kDa (Cep70 ) 的 centrosomal 蛋白质被归因于它 polyubiquitin 链的 deconjugation,为 Cep70 到的一个要求与 γ 交往;导管素并且在中心体本地化。另外, histone deacetylase 的调停 CYLD 的抑制 6 (HDAC6 ) ,它支持导管素 acetylation,为 CYLD 的睫的功能组成另一机制。HDAC6 的小分子的禁止者能部分在 CYLD 猛烈老鼠救睫的缺点。这些调查结果在 ciliogenesis 的调整强调蛋白质 ubiquitination 的重要性,作为这个过程的一个关键管理者识别 CYLD,并且建议在 ciliopathies 的 CYLD 缺乏的参与。 | Yunfan Yang Jie Ran Min Liu Dengwen Li Yuanyuan Li Xingjuan Shi Dan Meng Junmin Pan Guangshuo Ou Rim Aneja Sbao-Cong Sun Jun Zhou | 2014 | Cell Research2014，24，11： | 8 |
| 3 | The more the messier:centrosome amplification as a novel biomarker for personalized treatment of colorectal cancers显示文摘Colon cancer is currently the third most common cancer and second most fatal cancer in the United States,resulting in approximately 600,000 deaths annually.Though colorectal cancer death rates are decreasing by about 3%every year,disease outcomes could be substantially improved with more research into the drivers of colon carcinogenesis,the determinants of aggressiveness in colorectal cancer and the identification of biomarkers that could enable choice of more optimal treatments.Colon carcinogenesis is notably a slow process that can take decades.Known factors that contribute to the development of colon cancer are mutational,epigenetic and environmental,and risk factors include age,history of polyps and family history of colon cancer.Colorectal cancers exhibit heterogeneity in their features and are often characterized by the presence of chromosomal instability,microscopic satellite instability,or CpG island methylator phenotype.In this review,we propose that centrosome amplification may be a widespread occurrence in colorectal cancers and could potently influence tumor biology.Moreover,the quantitation of this cancer-specific anomaly could offer valuable prognostic information and pave the way for further customization of treatment based on the organellar profile of patients.Patient stratification models that take into account centrosomal status could thus potentially reduce adverse side effects and result in improved outcomes for colorectal cancer patients. | Monica M.Mahathre Padmashree C.G.Rida Ritu Aneja | 2016 | The Journal of Biomedical Research2016，30，6： | 3 |
| 4 | Diabetic Cardiomyopathy: Insights into Pathogenesis, Diagnostic Challenges, and Therapeutic Options显示文摘 | Ashish Aneja W.H. Wilson Tang Sameer Bansilal Mario J. Garcia Michael E. Farkouh | 2008 | The American Journal of Medicine2008，，9： | 3 |
| 5 | Liver Environment and HCV Replication Affect Human T-Cell Phenotype and Expression of Inhibitory Receptors显示文摘 | Daniela C. Kroy Donatella Ciuffreda Jennifer H. Cooperrider Michelle Tomlinson Garrett D. Hauck Jasneet Aneja Christoph Berger David Wolski Mary Carrington E. John Wherry Raymond T. Chung Kenneth K. Tanabe Nahel Elias Gordon J. Freeman Rosemarie H. de Kru | 2014 | Gastroenterology2014，，2： | 2 |
| 6 | 9-bromonoscapine induced mitotic arrest of cigarette smoke condensate-trans formed breast epithelial cells 显示文摘 | Jaiswal A S Aneja R Connors S K | 2009 | J Cell Biochem2009，106，6： | 1 |
| 7 | Obesity and hypertension 显示文摘 | El-Atat F Aneja A Mcfarlane S | 2003 | Endocrinol Metab Clin N Am2003，32，4： | 1 |
| 8 | Atmospheric transport and wet deposition of ammonium in North Carolina 显示文摘 | Walker J T Aneja V P Dickey D A | 2000 | Atmospheric Environment2000，34，20： | 1 |
| 9 | Influence of system variables on the morphological and dynamic mechanical behavior of polydimethylsiloxane based segmented polyurethane and polyurea copolymers:a comparative perspective显示文摘 | Jignesh P S Aneja A Wilkes G L | 2004 | Polymer2004，45，20： | 1 |
| 10 | Microbial Colonization of Beech and Spruce Litter-Influence of decomposition site and plant litter species on the diversity of microbial community显示文摘 | Aneja M Sharma S Flcischmann F Stich S Heller W Bahnweg G Munch J Schloter M | | 0，，01： | 1 |
| 11 | Sedation monitoring of children by the Bispectral Index in the pediatric intensive care unit 显示文摘 | Aneja R Heard AM Fletcher JE | 2003 | Pediatr Crit Care Med2003，4，1： | 1 |
| 12 | Natural sulfur emission into the atmosphere显示文摘 | ANEJA V P | 1990 | Journal of the Air Waste Management Association1990，40，： | 1 |
| 13 | Add-on melatonin improves quality of life in epileptic children on valproate monotherapy:a randomized,double-blind,placebo-controlled trial显示文摘 | Madhur Gupta Satinder Aneja Kamlesh kohli | 2004 | Epilepsy&Behavior2004，5，： | 1 |
| 14 | C-reactive protein predicts long-term mortality independently of low-density lipoprotein cholesterol in patients undergoing percutaneous coronary intervention显示文摘 | Louai Razzouk Paul Muntner Sameer Bansilal Annapoorna S. Kini Ashish Aneja Joshua Mozes Oana Ivan Madhavi Jakkula Samin Sharma Michael E. Farkouh | 2009 | American Heart Journal2009，，2： | 1 |
| 15 | Measurement and analysis of the relationship between ammonia, acid gases, and fine particles in eastern north Carolina显示文摘 | BAEK B H ANEJA V P | 2004 | Journal of the Air & Waste Management Association2004，54，5： | 1 |
| 16 | CSF interleukin-1 beta,tumor necrosis factor-alpha and free radicals production in relation to clinical outcome in acute baeterial meningitis显示文摘 | JAIN M ANEJA S MEHTA G | 2000 | Indian Pediatr2000，37，6： | 1 |
| 17 | CSF Interleukin-1 Beta,Tumor Necrosis Factor-alpha and Free Radicals Production in Relation to Clinical Outcome in Acute Bacterial Meningitis 显示文摘 | Jain M Aneja S Mehta G | 2000 | Indian Pediatr2000，37，6： | 1 |
| 18 | Diabetic cardiomyopathy : in- sights into pathogenesis, diagnostic challenges, and therapeutic op- tions显示文摘 | Aneja A Tang W H Bansilal S | 2008 | Am J Med2008，121，9： | 1 |
| 19 | Association between ad- mission neutrophil to lymphocyte ratio and outcomes in patients with a- cute coronary syndrome显示文摘 | Tamhane UU Aneja S Montgomery D | 2008 | Am J Cardiol2008，102，6： | 1 |
| 20 | Association between admission neutrophil to lymphocyte ratio and outcomes in patients with acute coronary syndrome 显示文摘 | TAMHANE U U ANEJA S MONTGOMERY D | 2008 | Am J Cardiol2008，102，： | 1 |
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