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| 1 | 印度Ganga-Meghna-Brahmaputra平原及周围地区与孟加拉国地下水砷污染及其对健康影响的19年研究显示文摘基于近19年对印度Ganga—Meghna—Brahmaputra(简称GMB)平原(面积569749km^2,人口超过5亿)地下水砷污染的调查,可以确定印度Ganga—Brahmaputra平原(包括北方邦、比哈尔邦、恰尔康得邦、西孟加拉邦、阿萨姆邦)和孟加拉国普遍受到砷的污染。近期的调查研究也表明,除米佐拉姆邦外,其他各邦的地下水也受到不同程度的砷污染。至今为止.已对印度各邦和孟加拧国的175000份和50808份压把井水样进行了含砷量检测。并组织了一支包括皮肤科、神经科和妇产科医生在内的有经验的专家组,对上述地区125000人进行了临床检查,其中9%患有砷导致的皮肤病损症状。至今共采集分析了60000份生物样品。包括发样、指甲、尿样及皮肤鳞屑,其中80%的样品含砷量超过允许值,很多人由此受到砷的亚临床损害。在上述砷暴露地区.19000名儿童经过检查,近1100人患有砷导致的皮肤病损。该调查结果表明.儿童比成人更容易受到砷的毒性损害。在这种状况下.应着力解决饮水安全问题来减轻砷的苊害. | Ahamed S Hossain MA Mukharjee A Sengupta MK Das B Nayak B Pal A Mukherjee SC Pati S Dutta RN Saha KC Quamruzzaman Q Chakraborti D 付松波(译) 孙殿军(审校) | 2007 | 中国地方病学杂志2007，26，1： | 3 |
| 2 | Mesuaferrea stem bark extract induces apoptosis and inhibits metastasis in human colorectal carcinoma HCT 116 cells, through modulation of multiple cell signalling pathways显示文摘Considering the great potential of natural products as anticancer agents, the present study was designed to explore the molecular mechanisms responsible for anticancer activities of Mesua ferrea stem bark extract against human colorectal carcinoma. Based on MTT assay results, bioactive sub-fraction(SF-3) was selected for further studies using HCT 116 cells. Repeated column chromatography resulted in isolation of less active α-amyrin from SF-3, which was identified and characterized by GC-MS and HPLC methods. α-amyrin and betulinic acid contents of SF-3 were measured by HPLC methods. Fluorescent assays revealed characteristic apoptotic features, including cell shrinkage, nuclear condensation, and marked decrease in mitochondrial membrane potential in SF-3 treated cells. In addition, increased levels of caspases-9 and-3/7 levels were also observed in SF-3 treated cells. SF-3 showed promising antimetastatic properties in multiple in vitro assays. Multi-pathway analysis revealed significant down-regulation of WNT, HIF-1α, and EGFR with simultaneous up-regulation of p53, Myc/Max, and TGF-β signalling pathways in SF-3 treated cells. In addition, promising growth inhibitory effects were observed in SF-3 treated HCT 116 tumour spheroids, which give a hint about in vivo antitumor efficacy of SF-3 phytoconstituents. In conclusion, these results demonstrated that anticancer effects of SF-3 towards colon cancer are through modulation of multiple molecular pathways. | Muhammad Asif Armaghan Shafaei Aman Shah Abdul Majid Mohammed Oday Ezzat Saad S Dahham Mohamed B.Khadeer Ahamed Chern Ein Oon Amin Malik Shah Abdul Majid | 2017 | Chinese Journal of Natural Medicines2017，15，7： | 2 |
| 3 | Friction and wear behaviour of cast A1 6063 based in situ metal matrix composites 显示文摘 | RAMESH C S AHAMED A | 2011 | Wear2011，271，： | 1 |
| 4 | Physicochemical and functional properties of Chenopodium quinoa starch显示文摘 | Singhal R S | 1996 | Carbohydrate Polymers1996，31，： | 1 |
| 5 | Neural-net controller for nonlinear plants:design approach through linearization显示文摘 | AHAMED M S TASADDUQ I A | 1994 | IEE Proceedings:Control Theory and Applications1994，141，5： | 1 |
| 6 | A reinforcement learning approach to automatic generation control显示文摘 | Rao P S N Sastry P S | 2002 | Electric Power Systems Research2002，63，1： | 1 |
| 7 | A reinforcement learning approach to automatic generation control显示文摘 | AHAMED T P NAGENDRA P S SASTRY P S | 2002 | Electric Power Systems Research2002，63，1： | 1 |
| 8 | Combined over-ex- pression of ehitinase and defensin genes in transgenic tomato en- hances resistance to Botrytis cinerea 显示文摘 | CHEN S C LIU A R AHAMMED G J | 2009 | African Joumal of Bio-technology2009，8，20： | 1 |
| 9 | Involvement of an efflux system in high-level fluoroquinolone resistance of Shigella dysenteriae显示文摘 | Ghosh A S Ahamed J Chauhan K K | 1998 | Biochem Biophys Res Commun1998，242，1： | 1 |
| 10 | Enhan-cing privacy and security of RFID system withserverless authentication and search protocols in per-vasive environments显示文摘 | Hoque M E Rahman F Ahamed S I | 2010 | Wireless Pers Commun2010，55，7： | 1 |
| 11 | The magnitude of arsenic contamination in groundwater and its health effects to the inhabitants of the Jalangi-one of the 85 arsenic affected blocks in West Bengal,India显示文摘 | Rahman MM Sengupta MK Ahamed S | 2005 | Sci Total Environ2005，338，3： | 1 |
| 12 | Synthesis and characterization of ball-milled nanocrystalline WC and nanocomposite WC-Co powders and subsequent consolidation 显示文摘 | Mahday A A Ahamed H A | 2000 | Journal of Alloys and Compounds2000，312，： | 1 |
| 13 | A reinforcement learning approach to automatic generation control显示文摘 | Imthias Ahamed T P Nagendra Rao P S Sastry P S | 2002 | Electric Power Systems Research2002，63，1： | 1 |
| 14 | Comparative evaluation of propolis and triantibiotic mixture as an intracanal medicament against enterococcus faecalis显示文摘 | Madhubala MM Srinivasan N Ahamed S | 2011 | J Endod2011，36，9： | 1 |
| 15 | Sta- bility Simulation of Six DOF manipulators using ADAMS and MAT- LAB显示文摘 | VENNISHMUTHU V AHAMMED S R RASHEETH H | 2014 | IOSR Journal of Engineering2014，4，3： | 1 |
| 16 | Dietary estrogens stimulate human breast cells cycle显示文摘 | Dees C Foster J S Ahammed S | 1997 | Envrion Health Perspect1997，，： | 1 |
| 17 | Enhancing privacy andsecurity of RFID system with serverless authentication and search protocols in pervasive environments 显示文摘 | Hoque M E Raham F Ahamed S I | 2010 | Wireless Per- sonal Cornmunications2010，55，1： | 1 |
| 18 | A trust-based secure service discovery (TSSD) model for pervasive computing显示文摘 | AHAMED S I SHARMIN M | 2008 | Journal of Computer Commu- nications2008，31，18： | 1 |
| 19 | Involvement of an effiux system in high-level fluoroquinolone resistance of Shigella dysenteriae显示文摘 | Ghosh A S Ahamed J Chauhan K K | 1998 | Biochem Biophys Res Commun1998，242，1： | 1 |
| 20 | Dietary estrogens stimulate human breast cells to enter the cell cycle显示文摘 | Dees C Foster JS Ahamed S | 1997 | Environ Health Perspect1997，105，3： | 1 |
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