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| 1 | Survival after inflammatory bowel disease-associated colorectal cancer in the Colon Cancer Family Registry显示文摘AIM: To investigate the survival of individuals with colorectal cancer (CRC) with inflammatory bowel disease (IBD-associated CRC) compared to that of individuals without IBD diagnosed with CRC. METHODS: Epidemiologic, clinical, and follow-up data were obtained from the Colon Cancer Family Registry (Colon CFR). IBD-associated cases were identified from self-report of physician diagnosis. For a subset of participants, medical records were examined to confirm self-report of IBD. Cox proportional hazards regression was applied to estimate adjusted hazard ratios (aHR) and 95%CI of mortality, comparing IBD-associated to non-IBD-associated CRC, adjusted for age at CRC diagnosis, sex, Colon CFR phase, and number of prior endoscopies. Following imputation to complete CRC stage information, adjustment for CRC stage was examined. RESULTS: A total of 7202 CRC cases, including 250 cases of IBD-associated CRC, were analyzed. Over a twelve year follow-up period following CRC diagnosis, 2013 and 74 deaths occurred among non-IBD associated CRC and IBD-associated CRC patients, respectively. The difference in survival between IBD-associated and non-IBD CRC cases was not statistically significant (aHR = 1.08; 95%CI: 0.85-1.36). However, the assumption of proportional hazards necessary for valid inference from Cox regression was not met over the entire follow-up period, and we therefore limited analyses to within five years after CRC diagnosis when the assumption of proportional hazards was met. Over this period, there was evidence of worse prognosis for IBD-associated CRC (aHR = 1.36; 95%CI: 1.05-1.76). Results were similar when adjusted for CRC stage, or restricted to IBD confirmed in medical records. CONCLUSION: These results support the hypothesis that IBD-associated CRC has a worse prognosis than non-IBD-associated CRC. | Scott V Adams Dennis J Ahnen John A Baron Peter T Campbell Steven Gallinger William M Grady Loic LeMarchand Noralane M Lindor John D Potter Polly A Newcomb | 2013 | World Journal of Gastroenterology2013，19，21： | 2 |
| 2 | Classification of multispectral images based on fractions of endmembers:Application to land-cover change in the Brazilian Amazon显示文摘 | Adams J B Sabol D E Kapos V | 1995 | Remote Sensing of Environment1995，52，2： | 1 |
| 3 | Chromosome 4q25 variants and atrial fibrillation recurrence after catheter ablation 显示文摘 | Husser D Adams V Piorkowski C | 2010 | J Am Coll Cardiol2010，55，8： | 1 |
| 4 | Sediment green- house gases (methane and carbon dioxide) in the Lobo-Broa Reservoir 显示文摘 | Abe D S Adams D D Galli C V S | 2005 | Lakes and Reservoirs: Research and Man- agement2005，10，4： | 1 |
| 5 | Impairment of carotidcardiacvagal baroreflex in wheelchair-dependent quadriplegics 显示文摘 | Convertino V A Adams W C Shea J D | 1991 | Am J Physiol1991，260，10： | 1 |
| 6 | Income inequlity and health:whatdoes the literature tell us显示文摘 | Adam W Eddy V D | 2000 | Public Health2000，，21： | 1 |
| 7 | A Coarse/Fine Search PN Code Acquisition Scheme显示文摘 | Adam C V Ronald D W Maximo H S | 2001 | IEEE Transactions on Aerospace and Electronic Systems2001，37，1： | 1 |
| 8 | Relations between the photoluminescence efficiency of CdTe nanocrystals and their surface properties revealed by synchrotron XPS显示文摘 | BORCHERT H TALAPIN D V GAPONIK N MCGINLEY C ADAM S LOBO A MOLLER T WELLER H | 2003 | J Phys Chem B2003，107，36： | 1 |
| 9 | Equity in health care finance and deli-very显示文摘 | Adam W Eddy V D | 2000 | Handbook of Health Economics2000，，1： | 1 |
| 10 | P-glicoprotein mediated resistence to 5'-nor-anhydrovinblastine(Navelbine)显示文摘 | Adams D J Knick V C | 1995 | Invest New Drugs1995，13，1： | 1 |
| 11 | Composition and activity of the microbial population in an acidic up land s oil and effects of liming显示文摘 | Shah Z Adams W A Haven C D V | 1990 | Soil Biology & Bi ochemistry1990，22，： | 1 |
| 12 | A method for the stress analysis of lap joints 显示文摘 | Adams R D Mallick V | 1992 | The Journal of Adhesion1992，38，34： | 1 |
| 13 | Growth of tourism in Nepal' s Everest region: Impact on the physical environment and structure of human settlements显示文摘 | Pawson I G Stanford D D Adams V A | 1984 | Mountain Research and Development1984，4，3： | 1 |
| 14 | Classification of multispectral images based on fraction endmembers,application to land cover change in the Brazilian Amazon显示文摘 | Adams J Sabol D Kapos V | 1995 | Remote Sens Environ1995，52，： | 1 |
| 15 | The combined effect of non-linear filtration and window size on the accuracy of tissue displacement estimation using detected echo signals 显示文摘 | Behar V Adam D | 2004 | Ultrasonics2004，11，： | 1 |
| 16 | Induction of diploid gynogenesis in southern flounder (Paralichthys lethostigma) with homologous and heterologous sperm显示文摘 | ADAM J L JOHN G HARRY V D | 2004 | Aquaculture2004，237，： | 1 |
| 17 | Analysis of semiconductor laser optical amplifiers 显示文摘 | Adams M J Collins J V Henning I D | 1985 | IEE Proceedings1985，132，1： | 1 |
| 18 | A review of research on the impact of professional learning communities on teaching practice and student learning 显示文摘 | Vescio V Ross D & Adams A | 2008 | Teaching and Teacher Education2008，，1： | 1 |
| 19 | Composition and Activity of the Microbial Population in an Acidic Upland Soil and Effects of Liming 显示文摘 | SHAH Z ADAMS W A HAVEN C D V | 1990 | Soil Biology& Biochemistry1990，22，： | 1 |
| 20 | Protease inhibitors of Manduce sexta expressed in transgenlc cotton显示文摘 | THOMAS J C ADAMS D G KEPPENNE V D | 1995 | Plant Cell Reporters1995，14，： | 1 |
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