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| 1 | Surgical treatment for liver cancer显示文摘Primary liver cancer is amongst the commonest tumors worldwide,particularly in parts of the developing world,and is increasing in incidence. Over the past three decades,surgical hepatic resection has evolved from a high risk,resource intensive procedure with limited application,to a safe and commonly performed operation with a range of indications. This article reviews the approach to surgical resection for malignancies such as hepatocellular cancer,metastatic liver de-posits and neuroendocrine tumors. Survival data after resection is also reviewed,as well as indications for curative resection. | Nicole C Tsim Adam E Frampton Nagy A Habib Long R Jiao | 2010 | World Journal of Gastroenterology2010,16,8: | 12 |
| 2 | Association between calcium sensing receptor gene polymorphisms and chronic pancreatitis in a US population:Role of serine protease inhibitor Kazal 1type and alcohol显示文摘AIM: To test the hypothesis that calcium sensing receptor (CASR) polymorphisms are associated with chronic pancreatitis (CP), and to determine whether serine protease inhibitor Kazal 1type (SPINK1) N34S oralcohol are necessary co-factors in its etiology. METHODS: Initially, 115 subjects with pancreatitis and 66 controls were evaluated, of whom 57 patients and 21 controls were predetermined to carry the high-risk SPINK1 N34S polymorphism. We sequenced CASR gene exons 2, 3, 4, 5 and 7, areas containing the majority of reported polymorphisms and novel mutations. Based on the initial results, we added 223 patients and 239 controls to analyze three common nonsynonymous single nucleotide polymorphisms (SNPs) in exon 7 (A986S, R990G, and Q1011E). RESULTS: The CASR exon 7 R990G polymorphism was signifi cantly associated with CP (OR, 2.01; 95% CI, 1.12-3.59; P = 0.015). The association between CASR R990G and CP was stronger in subjects who reported moderate or heavy alcohol consumption (OR, 3.12; 95% CI, 1.14-9.13; P = 0.018). There was no association between the various CASR genotypes and SPINK1 N34S in pancreatitis. None of the novel CASR polymorphisms reported from Germany and India was detected. CONCLUSION: Our United States-based study confirmed an association of CASR and CP and for the first time demonstrated that CASR R990G is a signifi cant risk factor for CP. We also conclude that the risk of CP with CASR R990G is increased in subjects with moderate to heavy alcohol consumption. | Venkata Muddana Janette Lamb Julia B Greer Beth Elinoff Robert H Hawes Peter B Cotton Michelle A Anderson Randall E Brand Adam Slivka David C Whitcomb | 2008 | World Journal of Gastroenterology2008,14,28: | 7 |
| 3 | 内皮Notch信号的抑制阻碍脂肪酸转运并导致成年心脏的代谢和血管重塑显示文摘营养成分在被肌肉细胞代谢利用之前通过内皮细胞转运。然而,对于内皮运输过程的调节知之甚少。Notch信号传导是发育过程中代谢和血管生成的关键调控因子。在该研究中,Jabs等研究了成年小鼠内皮Notch信号的遗传和药理学调控如何影响内皮脂肪酸转运、心脏血管生成和心脏功能。 | 刘青 叶鹏 Jabs M Rose AJ Lehmann LH Taylor J Moll I Sijmonsma TP Herberich SE Sauer SW Poschet G Federico G Mogler C Weis EM Augustin HG Yan M Gretz N Schmid RM Adams RH Gr9ne HJ Hell R Okun JG Backs J Nawroth PP Herzig S Fischer A | 2018 | 中华高血压杂志2018,26,3: | 6 |
| 4 | Barrett’s metaplasia glands are clonal, contain multiple stem cells and share a common squamous progenitor显示文摘 | Anna M Nicholson Trevor A Graham Ashley Simpson Adam Humphries Nicola Burch Manuel Rodriguez-Justo Marco Novelli Rebecca Harrison Nicholas A Wright Stuart A C McDonald Janusz A Jankowski | 2012 | Gut2012,,10: | 3 |
| 5 | The Stroke Outcomes and Neuroimaging of Intracranial Atherosclerosis (SONIA) Trial显示文摘 | E Feldmann J L. Wilterdink A Kosinski M Lynn M I. Chimowitz J Sarafin H H. Smith F Nichols J Rogg H J. Cloft L Wechsler J Saver S R. Levine C Tegeler R Adams M Sloan | 2007 | Neurology2007,,24: | 2 |
| 6 | Adipocyte iron regulates adiponectin and insulin sensitivity显示文摘 | Gabrielsen J Scott Gao Yan Simcox Judith A Huang Jingyu Thorup David Jones Deborah Cooksey Robert C Gabrielsen David Adams Ted D Hunt Steven C Hopkins Paul N Cefalu William T McClain Donald A | 2012 | EN2012,,10: | 2 |
| 7 | Comparison of the effects of an angiotensin-converting enzyme inhibitor and a vasopeptidase inhibitor after myocardial infarction in the rat显示文摘 | Lapointe N Blais C Jr Adam A | 2002 | J Am Coll Cardiol2002,39,10: | 2 |
| 8 | Bee Parasitic Mite Syndrome(II):The Role of Varroa Mite and Virues 显示文摘 | Hung A C F Adams J R Shimanuki H | 1995 | American Bee Journal1995,12,: | 2 |
| 9 | A theory for the ablation of glassy materials显示文摘 | BETHE H A ADAMS M C | 1959 | Journal of the Aero/Space Sciences1959,26,6: | 1 |
| 10 | Decomposition of surface EMG signals 显示文摘 | DE LUCA C J ADAM A WOTIZ R | 2006 | Journal of Neurophysiology2006,96,3: | 1 |
| 11 | Update on family psychoeducation for schizophrenia显示文摘 | Dixon L Adams C Lucksted A | 2000 | Schizoph Bull2000,26,11: | 1 |
| 12 | The environmental fate of phthalate esters: a literature review显示文摘 | Stales C A Peterson D R Parkerton T F Adams W J | 1997 | Chemosphere1997,35,4: | 1 |
| 13 | Transient homodynamic effect of recruitment maneuvers in three experimental models of acute lung injury显示文摘 | Lin S C Adams A B Sinonson D A | 2004 | Crit Care Med2004,32,12: | 1 |
| 14 | Short - channel effects and drain - induced barrier lowering in nanometerscale GaAs MESFET's 显示文摘 | James A Adams Thayne I G Wilkinson C D W | 1993 | IEEE Trans Electron Devices1993,40,6: | 1 |
| 15 | Trade offs between the persistence of foliage and productivity in two Pinus species显示文摘 | Warren C R Adams M A | | 0,,: | 1 |
| 16 | The environmental fate of phthalate esters: a literature review 显示文摘 | Stales C A Peterson D R Parkerton T F Adams W J | 1997 | Chemosphere1997,35,4: | 1 |
| 17 | Postoperative pain management in orthopaedic patients: no differences in pain score,but improved stress control by epidural anaesthesia显示文摘 | Adams H A Saatweber P Schmitz C S | 2002 | Eur J Anaesthesiol2002,19,9: | 1 |
| 18 | CEO turnover and bondholder wealth 显示文摘 | Adams J C Mansi S A | 2009 | Journal of Banking & Finance2009,33,3: | 1 |
| 19 | Food consumption risks associated with animal clones: What should be investigated显示文摘 | RUDENKO L MATHESON J C ADAMS A L | 2004 | Cloning Stem Cells2004,6,2: | 1 |
| 20 | Comparison of several sulfluramid bait formulations for control of the red imported fire ant (Hymenoptera:Fotmicidae)显示文摘 | Banks W A Las A S Adams C T | 1992 | Journal of Entomological Science1992,27,: | 1 |