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| 1 | Persistent alanine aminotransferase elevation among the general Iranian population: Prevalence and causes显示文摘AIM: To determine the prevalence and causes of persistently elevated alanine aminotransferase (ALT) levels among the general population in northern Iran. METHODS: A total of 2292 (1376 female, aged 18-75 year), were selected by systematic clustered random sampling from the cities and villages of Gonbad and Kalaleh in Golestan Province and invited to participate in the study. A comprehensive history regarding alcohol drinking and medication was taken. Body mass index (BMI), viral markers and ALT levels were measured. If ALT level was ≥ 40 U/L, it was rechecked twice within 6 mo. Those with ≥ 2 times elevation of ALT were considered as having persistently elevated ALT level. Non-alcoholic fatty liver disease (NAFLD) was diagnosed based on evidence of fatty liver upon sonography and excluding other etiology. RESULTS: A total of 2049 (1351 female) patients participated in the study, 162 (7.9%) had elevated ALT level at the first measurement. Persistently elevated ALT level was detected in 64 (3.1%) participants, with51 (79.6%) with no obvious etiology, six (9.3%) with Hepatitis B, four (6.2%) with Hepatitis C virus (HCV) infection and three (4.6%) with alcoholic hepatitis. The prevalence of NAFLD and alcoholic hepatitis was 2.04% (42 patients) and 0.1% (three), respectively. There was correlation between NAFLD and male gender, overweight, diabetes and living in an urban area [odds ratio = 3.03 (95% CI: 1.6-5.72), 4.21 (95% CI: 1.83-9.68), 2.86 (95% CI: 1.05-7.79) and 2.04 (95% CI: 1.00-4.16) respectively]. CONCLUSION: NAFLD is the most common cause of persistently elevated serum ALT level among the general population of Iran. | Raika Jamali Mahmoodreza Khonsari Shahin Merat Masoud Khoshnia Elham Jafari Alireza Bahram Kalhori Hassan Abolghasemi Sedighe Amini Mahtab Maghsoudlu Mohammad Reza Deyhim Houri Rezvan Akram Pourshams | 2008 | World Journal of Gastroenterology2008，14，18： | 7 |
| 2 | Serum γ-glutamyltransferase,alanine aminotransferase,and aspartate aminotransferase activity in Iranian healthy blood donor men显示文摘AIM: To determine serum γ-glutamyltransferase (GGT), alanine aminotransferase (ALT), and aspartate aminotransferase (AST) activity, and to assess their correlation with demographic and clinical findings in healthy blood donors. METHODS: This cross-sectional study was performed in 934 male blood donors, aged 18 to 68 years, who consecutively attended Tehran blood transfusion service in 2006. All participants were seronegative for HBV or HCV infections, non alcohol users, and all underwent a standard interview and anthropometric tests. Clinical and biochemical parameters including AST, ALT, and GGT activities were determined. Patients taking drugs known to cause hepatic fat deposition were excluded. For AST, ALT, and GGT variables, we used 33.33 and 66.66 percentiles, so that each of them was divided into three tertiles. RESULTS: Mean AST, ALT, and GGT activities were 25.26 ± 12.58 U/L (normal range 5-35 U/L), 33.13 ± 22.98 (normal range 5-35 U/L), and 25.11 ± 18.32 (normal range 6-37 U/L), respectively. By univariate analyses, there were significant associations between increasing AST, ALT, or GGT tertiles and age, body weight, body mass index, and waist and hip circumferences (P < 0.05). By multiple linear regression analyses, ALT was found to be positively correlated with dyslipidemia (B = 6.988, P = 0.038), whereas ALT and AST were negatively correlated with age. AST, ALT, and GGT levels had positive correlation with family history of liver disease (B = 15.763, P < 0.001), (B = 32.345, P < 0.001), (B =24.415, P < 0.001), respectively.CONCLUSION: Although we did not determine the cutoffs of the upper normal limits for AST, ALT, and GGT levels, we would suggest screening asymptomatic patients with dyslipidemia and also subjects with a family history of liver disease. | Hossein Khedmat Farahnaz Fallahian Hassan Abolghasemi Bashir Hajibeigi Zohre Attarchi Farshid Alaeddini Mohammad Taghi Holisaz Masoumeh Pourali Shahin Sharifi Nasrin Zarei | 2007 | World Journal of Gastroenterology2007，13，6： | 7 |
| 3 | Strontium Adsorption from Sulfuric Acid Solution by Dowex 50W-X Resins显示文摘在这研究,从由不同 Dowex 50W-X 离子交换树脂的硫磺的酸答案的锶吸附被调查。在这些树脂之中, Dowex 50W-X8 树脂从水的答案显示出锶的最大的吸着。pH,接触时间,树脂的团,温度,和锶吸附上的介入的离子的集中的效果被评估决定锶吸着过程的最佳条件。吸着的运动模型用伪 first 和伪秒顺序模型被分析。结果显示伪秒命令运动模型比另一个更适当。而且,在这研究获得的数据被适合进几个吸着等温线模型,兰米尔吸着等温线显示出最好的试穿到试验性的数据,这被发现。 | Meisam Hafizi Hossein Abolghasemi Morteza Moradi Saeed Alamdar Milani | 2011 | Chinese Journal of Chemical Engineering2011，19，2： | 4 |
| 4 | A gradient-based alternating minimization approach for optimization of the measurement matrix in compressive sensing显示文摘 | Abolghasemi V Ferdowsi S and Sanei S | 2012 | Signal Pro- cessing2012，92，3： | 1 |
| 5 | Comparison of resili- ence,positive/negative affect, and psychological vulnerability be- tween Iranian infertile and fertile men显示文摘 | Abolghasemi A Rajabi S Sheikhi M | 2013 | Iran J Psychiatry Behav Sci2013，7，1： | 1 |
| 6 | The accuracy of the Raypex5 electronic apex locator using stainless-steel hand K-file versus nickel-titanium rotary Mtwo file 显示文摘 | Sadeghi S Abolghasemi M | 2010 | Med Oral Patol Oral Cir Bucal2010，15，5： | 1 |
| 7 | A particle swarm optimiza- tion algorithm for open vehicle routing problem 显示文摘 | MirHassani S A Abolghasemi N | 2011 | Expert Systems with Applications2011，38，11： | 1 |
| 8 | A gradient- based alternating minimization approach for optimi- zation of the measurement matrix in compressive sensing显示文摘 | Abolghasemi V Ferdowsi S Sanei S | 2012 | Signal Processing2012，92，3： | 1 |
| 9 | Kinetics of Au ( HI ) extraction by DBC from hydro-chloric solution using Lewis cell显示文摘 | JAVANSHIR S ABDOLLAHY M ABOLGHASEMI H | 2011 | Int J Miner Process2011，98，1： | 1 |
| 10 | Token Reinforcement Therapeutic Approach is More Effective than Exercise for Controlling Negative Symptoms of Schizophrenic Patients:A Randomized Controlled Trial显示文摘 | Gholipour A Abolghasemi SH Gholinia K | 2012 | Int J Prev Med2012，3，7： | 1 |
| 11 | Estimating blood transfusion requirements in preparation for a majorearthquake:the Tehran,Iran study显示文摘 | Tabatabaie M Ardalan A Abolghasemi H | 2010 | Prehosp Disaster Med2010，25，3： | 1 |
| 12 | Token reinforcement ther- apeutic approach is more effective than exercise for controlling neg- ative symptoms of schizophrenic patients:a randomized controlled trial显示文摘 | Gholipour A Abolghasemi S Gholinia K | 2012 | International J Preventive Medicine2012，3，： | 1 |
| 13 | The Effect of Irrigating So- lutions on the Accuracy of the Raypex5 Apex Locator 显示文摘 | Shiva Sadeghi Masoumeh Abolghasemi | 2008 | Dent Res J2008，5，1： | 1 |
| 14 | Silica aerogel-glass fiber composites as fire shield for steel frame structures显示文摘 | Motahari S Abolghasemi A | 2015 | Joumal of Materials in Civil Engineering2015，27，10： | 1 |
| 15 | gradient-based alternating minimization approach for optimization of the measurement matrix in compressive sensing显示文摘 | Abolghasemi V Ferdowsi S Sanei S | 2012 | Signal Processing2012，92，4： | 1 |
| 16 | A particle swarm optimization algorithm for open vehicle routing problem显示文摘 | MirHassani S A Abolghasemi N | 2011 | Expert Systems with Applications2011，38，11： | 1 |
| 17 | The comparison of the behaviors of polymer/clay nanocomposites based on higt dendity polyethylene and polypropylenein exposure of electron-irradiation显示文摘 | MOHADDESPUR A AHMADI S J ABOLGHASEMI H | 2010 | Polymer Composites2010，31，1： | 1 |
| 18 | The accuracy of the Raypex5 electronic apex locator using stainless-steel hand K-file versus nick- el-titanium rotary Mtwo file 显示文摘 | Shiva Sadeghi Masoomeh Abolghasemi | 2010 | Med Oral Patol Oral Cir Bucal2010，915，5： | 1 |
| 19 | Revisiting blood transfusion preparedness:Experience from the Barn earthquake response显示文摘 | Abolghasemi H Radfar M H Tabatabaee M | | 0，，05： | 1 |
| 20 | A calmagite immobilized agarose membrane optical sensor for selective monitoring of Cuz+ 显示文摘 | Hashemi P Abolghasemi M M Alizadeh K | 2008 | Sens Actuators B2008，129，： | 1 |
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