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| 1 | Evaluation of patients with dry eye disease for conjunctival Chlamydia trachomatis and Ureaplasma urealyticum显示文摘AIM:To determine the possibility of the development of dry eye disease(DED) as a result of persistent infection with Chlamydia trachomatis and Ureaplasma urealyticum in the conjunctiva of patients.METHODS: This study was conducted on 58 patients of age range 20-50 y,diagnosed with DED confirmed by Schirmer I test and tear breakup time.The non-dry eye control group included 27 subjects of the same age.Ocular specimens were collected as conjunctival scrapings and swabs divided into three groups: the first used for bacterial culture,the second and third taken to detect Chlamydia trachomatis and Ureaplasma urealyticum by direct fluorescent antibody(DFA) assay and polymerase chain reaction(PCR) method. RESULTS: Chlamydia trachomatis was detected in 65.5% and 76% of DED patients by DFA and PCR methods respectively.Ureaplasma urealyticum was found in 44.8% of DED infected patients using the PCR method.Both organisms were identified in only 37.9% of DED patients found to be infected.Control subjects had a 22%detection rate of Chlamydia trachomatis by DFA assay versus a 7% detection rate by PCR; while Ureaplasma urealyticum was detected in 3.7% of the controls by PCR method.The conjunctival culture revealed that gram positive microorganisms represented 75% of isolates with coagulase negative Staphylococci the most common(50%) followed by Staphylococcus aureus(20%),whereas gram negative microorganisms occurred in 25% of cases,isolating Moraxella spp.as the most frequent organism. CONCLUSION: Our results tend to point out that Chlamydia trachomatis and Ureaplasma urealyticum were detected in a moderate percentage of patients with DED,and could be a fair possibility for its development.PCR is more reliable in detecting Chlamydia trachomatis than DFA technique.The presence of isolated conjunctival bacterial microflora can be of some potential value. | Maha Mohssen Abdelfattah Rania Abdelmonem Khattab Magda H.Mahran Ebrahim S.Elborgy | 2016 | International Journal of Ophthalmology(English edition)2016，9，10： | 6 |
| 2 | SMILE intraoperative complications: incidence and management显示文摘AIM: To report the intraoperative complications associated with small incision lenticule extraction(SMILE) and their management. METHODS: This was a retrospective consecutive interventional clinical study, carried out on patients with myopia and myopic astigmatism, who underwent SMILE procedure. Type of intraoperative complications and their management were recorded. RESULTS: Our study comprised 282 eyes of 141 patients who were enrolled for SMILE surgeries. The intraoperative complications included lost vacuum(18 eyes, 6.38%), treatment decentration(6 eyes, 2.12%), wound bleeding(21 eyes, 7.45%), incomplete bubble separation(black islands)(3 eyes, 1.06%), the epithelial defects(15 eyes, 5.32%). Incision tear(27 eyes, 9.57%), lenticule adherence to the cap(6 eyes, 2.12%), and cap perforation occurred in 2 eyes(0.7%). CONCLUSION: Although SMILE is a promising technique for the correction of myopia and myopic astigmatism with predictable, efficient, safe refractive and visual outcomes, complications can occur. However, most of them are related to inexperience and are included in the learning curve of the technique. More studies with a bigger number of eyes are required to efficiently evaluate the intraoperative complications and standardize their management strategies. | Abdelmonem M Hamed Mohamed Amin Heikal Tarek T.Soliman Ahmed Daifalla Khaled E Said-Ahmed | 2019 | International Journal of Ophthalmology(English edition)2019，12，2： | 4 |
| 3 | Anatomy and embryology of umbilicus in newborns: a review and clinical correlations显示文摘脐在新生儿被认为腹部的一面镜子。尽管有它的重要性,脐与许多身体系统作为分离题目在文学和课本被说了,例如尿、消化、心血管的。这篇文章试图在一个综合话题下面在与临床的混乱的关系探讨脐的基本知识在估计新生儿和婴儿帮助医生和外科医生。脐象合拢胚胎的板发生的胎儿的生活的第四个星期一样早出现。脐开始作为一枚原始脐的戒指出现在身体的腹的方面上。原始的脐包含连接的梗,脐的容器,卵黄肠的管和容器,尿囊,和循环。变化发生形成权威的绳索,也就是,它包含三个脐的容器一根静脉和二根动脉,在 Whartons 嵌入果冻。在出生以后,在身体内的脐的容器涂抹并且逐渐地形成系带。在脐的先天的混乱包括形成疝,流血,并且排出有粘液,尿,或排汇物。一些这些混乱要求突现的外科的干扰,而其它可以保存地被管理。脐有许多胚胎学的残余。因此,脐对各种各样的临床的混乱敏感。尽早检测这些混乱是必要的阻止或最小化可能的复杂并发症。 | Abdelmonem A. Hegazy | 2016 | Frontiers of Medicine2016，10，3： | 3 |
| 4 | Study of the prevalence and association of ocular chlamydial conjunctivitis in women with genital infection by Chlamydia trachomatis, Mycoplasma genitalium and Candida albicans attending outpatient clinic显示文摘AIM: To determine the association between chlamydial conjunctivitis and genital infection by Chlamydia trachomatis, Mycoplasma genitalium and Candida albicans, in addition to the possible relationship between cultured bacterial pathogens and oculogenital chlamydial infection.METHODS: This study was performed on 100(50 symptomatic and 50 asymptomatic) women attending the Gynecological and Obstetric outpatient clinic of Alzahra hospital, Alazhar University. Simultaneously a conjunctival swab was taken from these patients.Polymerase chain reaction(PCR) was done on DNA extracted from both vaginal and conjunctival swab samples. Culture for both vaginal and conjunctival swabs was also done.RESULTS: Candida albicans was the predominant organism isolated by culture in 20% and 40% of conjunctival and vaginal swabs respectively. By the PCR method, ocular Chlamydia trachomatis was present in 60% of symptomatic women, while genital Chlamydia trachomatis infection was present in 30% of symptomatic women. The results of this method also indicated that 25/50(50%) vaginal swabs were positive with PCR for Candida albicans versus 15/50(30%) were PCR positive in conjunctival swab. Mycoplasma genitalium was present in only 10% of vaginal swabs.Concomitant oculogenital PCR positive results for Chlamydia trachomatis and Candida albicans were 30% and 28% respectively.CONCLUSION: Ocular Chlamydia trachomatis was associated with genital Chlamydia trachomatis in a high percentage of women followed by Candida albicans.Cultured bacterial organisms do not play a role in enhancement of Chlamydia trachomatis infection. | Rania Abdelmonem Khattab Maha Mohssen Abdelfattah | 2016 | International Journal of Ophthalmology(English edition)2016，9，8： | 2 |
| 5 | 反复使用抗生素患者结膜菌群的变化及耐药模式研究(英文)显示文摘目的:观察和分析反复使用抗生素患者结膜菌群的变化。此外,确定这种反复暴露对结膜菌群抵抗模式的影响。方法:研究纳入40例眼科研究所视网膜科患者。所有受试者至少进行了连续4次、每月一次的玻璃体腔注射(IVI),其中一些患者根据需要延长至6mo或1y。将患者随机分为3组,每组给予氧氟沙星、莫西沙星或头孢他啶任意一种抗生素。使用Kirby-Bauer扩散法对所有细菌进行药敏试验。结果:研究中,以表皮葡萄球菌(51.2%)为主,其次是金黄色葡萄球菌(14%),微球菌(12.8%)和其他凝固酶阴性葡萄球菌(CONS)占13%。结果显示,在4次随访中,与随机接受头孢他啶治疗的患者的基线培养相比,接受头孢他啶治疗的患者眼部表皮葡萄球菌的百分比有所增加。相比之下,与基线相比,金黄色葡萄球菌的百分比没有明显增加。在氟喹诺酮治疗眼中观察到表皮葡萄球菌的百分比从基线增加。与头孢他啶治疗组相比,氟喹诺酮治疗组的金黄色葡萄球菌百分比较基线升高。然而,随着新一代和老一代氟喹诺酮类药物的暴露,眼部菌群组成模式发生了变化。我们注意到,从基线开始,莫西沙星治疗组比氧氟沙星治疗组的表皮葡萄球菌增多。暴露于老一代和新一代氟喹诺酮类药物的金黄色葡萄球菌的模式没有差异。结论:反复使用眼用抗生素不仅会改变正常眼部菌群的组成,还会选择耐药菌株。 | Rania Abdelmonem Khattab Maha Abdelfattah Iman Fahmy | 2019 | 国际眼科杂志2019，19，11： | 2 |
| 6 | Expression levels of pro-inflammatory interleukin-8 and certain antimicrobial peptides in concurrent with bacterial conjunctivitis显示文摘AIM:To detect the quantitative expression levels of the pro-inflammatory interleukin-8(IL8),antimicrobial peptides human beta defense-2(HBD2),and human beta defense-3(HBD3)genes in bacterial conjunctivitis.METHODS:The human conjunctival epithelial cells were obtained using the impression cytology technique from healthy controls and patients.The genes expression levels were determined utilizing a reverse transcription quantitative polymerase chain reaction(RT-q PCR).The contribution of causative agent type,the number of isolates and severity of clinical features,in the increase of genes expression was also determined.RESULTS:The RT-q PCR showed that IL8,HBD2,and HBD3 expression increased in bacterial conjunctivitis as compared to healthy control(P<0.001).In gram-negative bacterial conjunctivitis,HBD2 was highly up-regulated(P<0.001)compared to other types of bacterial conjunctivitis.In mixed bacterial conjunctivitis,a direct correlation between HBD2 up-regulation and HBD3 up-regulation was observed(P<0.05).The severity of clinical features was related to the up-regulation of IL8 and HBD2(P<0.05).CONCLUSION:IL8,HBD2,and HBD3 are immuneeffectors in infectious conjunctivitis.HBD2 is active during different bacterial conjunctivitis but is more released with gram-negative bacteria compared to gram-positive bacteria.HBD3 is an obvious defender in different bacterial conjunctivitis. | Alaa El-Dien Shawky Hosny Zeinab El-Demerdash El-Bazza Mohammed Abdelhalim Ramadan Maha Ahmed Shafik Mahmoud Ahmed Shafeek Rania Abdelmonem Khattab | 2021 | International Journal of Ophthalmology(English edition)2021，14，5： | 2 |
| 7 | Decreased expression of DNA-dependent protein kinase,a DNA repair protein,during human colon carcinogenesis显示文摘 | BASIL R SIMONA B ABDELMONEM E | 2001 | Cancer Res2001，61，1： | 1 |
| 8 | A Method for Evaluating the Effects of Performance Degradation on Communicaion Network Applicaions显示文摘 | Abdelmonem A H Ryzin G J V | 1990 | IEEE1990，，： | 1 |
| 9 | Decreased expression of DNA-dependent protein kinase, a DNA repair protein, during human colon carcinogenesis显示文摘 | BASIL R SIMONA B ABDELMONEM E | 2001 | Cancer Res2001，61，23： | 1 |
| 10 | Observational comparison of abdominal,vaginal and laparoscopic hysterectomy as performed at a university teaching hospital显示文摘 | Abdelmonem A Wilson H Pasic R | 2006 | J Reprod Med2006，51，12： | 1 |
| 11 | Decreased expression of DNA-dependent protein kinase,a DNA repair protein,during human colon carcinogenesis显示文摘 | Basil R Simona B Abdelmonem E | 2001 | Cancer Res2001，61，23： | 1 |
| 12 | Observational comparison of abdominal, vaginal and laparoscopic hysterectomy as performed at a university teaching hospital显示文摘 | Abdelmonem A Wilson H Pasic R | 2006 | J Reprod Med2006，51，12： | 1 |
| 13 | Thermal cracking of rapeseed oil as alternative fuel显示文摘 | Abdelmonem N M Nabil D M | 2004 | Energy Sources2004，26，11： | 1 |
| 14 | Observational comparison of abdominal,vaninal and laparoscopic hysterectomy as performed at a university teaching hospital显示文摘 | Abdelmonem A Wilson H Pasic R | 2006 | J Reprod Med2006，51，12： | 1 |
| 15 | Observational comparison of abdominal,vaginal and laparoscopic hysterectomy as performed at a university teaching hospital显示文摘 | Abdelmonem A Wilson H Pasic R | 2006 | J Reprod Med2006，51，12： | 1 |
| 16 | Observational comparison of abdominal vaginal and Iaparoscopic hysterectomy as performed at a university teachin: hosoital显示文摘 | Abdelmonem A Wilson H Pasic R | 2006 | J Reprod Med2006，51，12： | 1 |
| 17 | New source - moderator geometry to improve per- fonnance of 252Cf and 241Am - Be source - based PGNAA setups 显示文摘 | Naqvi A A Abdelmonem M S A1- Misned G et al | 2006 | Nuclear Instruments and Methods in Physics Research Section A: Accelerators Spec- trometers Detectors and Associated Equipment2006，562，1： | 1 |
| 18 | The effect of nanoparticle degradation on poly( methacrylic acid) - coated duantum dot toxicity:the importance of particle functionality assess- ment in toxicology显示文摘 | SOENEN SJ MONTENEGRO JM ABDELMONEM AM | 2014 | Acta Biomater2014，10，： | 1 |
| 19 | A full wave analysis of microstrip - to - waveguide transition 显示文摘 | Yao Hui - Wen Abdelmonem Amr Liang Ji - Fuh | 1994 | IEEE MTT- S Digest1994，2，1： | 1 |
| 20 | The effect of nanoparticle degradation on poly(methacrylic acid)-coated quantum dot toxicity: The importance of particle functionality assessment in toxicology显示文摘 | Soenen S J Montenegro JM Abdelmonem AM | 2014 | Acta Biomaterialia2014，10，2： | 1 |
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