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| 1 | 静脉血栓栓塞症的抗血栓治疗:美国《胸科学》杂志指南显示文摘包括深静脉血栓和肺栓塞在内的静脉血栓栓塞症是癌症患者的主要并发症,发生率为4%~20%,并且是常见的潜在致命性急症。本文介绍了美国《胸科学》杂志指南中VET的抗血栓治疗的部分内容,其以第9版《美国胸内科医师学会循证临床实践指南》中的《静脉血栓栓塞症的抗血栓治疗:抗血栓治疗和阻止血栓形成》一文为参照,基于静脉血栓栓塞症治疗的Ⅲ期试验的发表年份,对口服抗凝剂(达比加群、利伐沙班、阿哌沙班、依度沙班)进行先后阐述(但是这一排序并不是指南专家组对药剂的优劣排序),以为临床医生提供参考。 | Kearon C Akl EA Ornelas J Blaivas A Jimenez D Bounameaux H Huisman M King CS MorrisT Sood N Stevens SM Vintch JRE Wells P Woller SC Moores CL 本刊编辑部 | 2016 | 中国全科医学2016，19，9： | 10 |
| 2 | SLC26A4 mutation testing for hearing loss associated with enlargement of the vestibular aqueduct显示文摘Pendred syndrome(PS) is characterized by autosomal recessive inheritance of goiter associated with a defect of iodide organification, hearing loss, enlargement of the vestibular aqueduct(EVA), and mutations of the SLC26A4 gene. However, not all EVA patients have PSor SLC26A4 mutations. Two mutant alleles of SLC26A4 are detected in 1/4 of North American or European EVA populations, one mutant allele is detected in another 1/4 of patient populations, and no mutations are detected in the other 1/2. The presence of two mutant alleles of SLC26A4 is associated with abnormal iodide organification, increased thyroid gland volume, increased severity of hearing loss, and bilateral EVA. The presence of a single mutant allele of SLC26A4 is associated with normal iodide organification, normal thyroid gland volume, less severe hearing loss and either bilateral or unilateral EVA. When other underlying correlations are accounted for, the presence of a cochlear malformation or the size of EVA does not have an effect on hearing thresholds. This is consistent with observations of an Slc26a4 mutant mouse model of EVA in which hearing loss is independent of endolymphatic hydrops or inner ear malformations. Segregation analyses of EVA in families suggest that the patients carrying one mutant allele of SLC26A4 have a second, undetected mutant allele of SLC26A4, and the probability of a sibling having EVA is consistent with its segregation as an autosomal recessive trait. Patients without any mutations are an etiologically heterogeneous group in which siblings have a lower probability of having EVA. SLC26A4 mutation testing can provide prognostic information to guide clinical surveillance and management, as well as the probability of EVA affecting a sibling. | Taku Ito Julie Muskett Parna Chattaraj Byung Yoon Choi Kyu Yup Lee Christopher K Zalewski Kelly A King Xiangming Li Philine Wangemann Thomas Shawker Carmen C Brewer Seth L Alper Andrew J Griffith | 2013 | World Journal of Otorhinolaryngology2013，3，2： | 2 |
| 3 | Pulmonary complications after esophagectomy显示文摘 | Christopher E Avendano Patrick A Flume Gerard A Silvestri Lydia B King Carolyn E Reed | 2002 | The Annals of Thoracic Surgery2002，，3： | 2 |
| 4 | The Baffled Flask Test for Dispersant Effectiveness: A Round Robin Evaluation of Reproducibility and Repeatability显示文摘 | Albert D Venosa Dennis W King George A Sorial | 2002 | Spill Science and Technology Bulletin2002，，5： | 2 |
| 5 | Heterogeneity of the genome-linked protein of FMDV显示文摘 | King A M Q Anger T J R Brown F | 1980 | J Virol1980，34，： | 2 |
| 6 | Pedagogical content knowing:An integrative model for teacher preparation显示文摘 | Cochran Kathryn F DeRuiter James A King Richard A | 1993 | Journal of Teacher Education1993，44，4： | 1 |
| 7 | Flight Control Actuation Technology for Next--Generation All-- Electric Aircraft显示文摘 | Botten S L Whitley C R King A D | 2000 | Technology Review Journal-- Millennium Issue2000，，3： | 1 |
| 8 | Photoperiodic induction and inheritance of diapause in Pionea forficalis ( Lepidoptera: Pyralidae) 显示文摘 | King A B S | 1974 | Entomol Exp Appl1974，17，： | 1 |
| 9 | phenomena of scintillation noise in radar-tracking system显示文摘 | Dunn J H Howard D D king A M | 1959 | Proceedings of IRE1959，47，5： | 1 |
| 10 | Usefulness of ovarian volume and cysts in female is osexual precocbus puberty 显示文摘 | KING L R SIEGE I M J SOBMON A L | 1993 | J Ultrasound in Medicine1993，12，10： | 1 |
| 11 | Surface expression of HLA-C antigen by human extravillous trophoblast 显示文摘 | King A TD Burrows SE Hiby S | 2000 | Placenta2000，21，： | 1 |
| 12 | Anthocyanin, phenolic composition, colour measurement and sensory analysis of BC commercial red wines显示文摘 | CLIFF M A KING M C SCHLOSSER J | 2007 | Food Research International2007，40，1： | 1 |
| 13 | Prior Political Experience and Gubernatorial Popularity 显示文摘 | King J D Hamman J A Cohen J E | 2005 | Presented at the Fifth Annual State Polities and Policy Conference East Lansing Michigan2005，，： | 1 |
| 14 | On edge detection of X -ray images using fuzzy sets显示文摘 | PAL S K KING R A | 1983 | IEEE Trans Part Analand Machine Intell1983，5，1： | 1 |
| 15 | Schematic method of deriving the rate laws for enzyme-catalyzed reactions显示文摘 | King E L Altman C A | 1956 | J Phys Chem1956，60，： | 1 |
| 16 | Assembly of foot-and- mouth disease virus empty capids synthesized by a vaccinia virus expression system显示文摘 | Abrams C C King A M Belsham G J | 1995 | J Gen Virol1995，76，： | 1 |
| 17 | The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues显示文摘 | Lindsten T Ross AJ King A | 2000 | Mol Ce112000，6，： | 1 |
| 18 | Decidual natural-killer-cell interaction with trophoblaster: cytolysis or cytokine production 显示文摘 | Loke YW King A | 2000 | Biochem Soc Trans2000，28，3： | 1 |
| 19 | Sulfonamide resistance in Haemophilus influenzae mediated by acquisition of sul2 or a short insertion in chromosomal folP显示文摘 | Enne VI King A Livermore DM | 2002 | Antimicrob Agents Chemother2002，46，6： | 1 |
| 20 | Cell cycle and apoptosis:common pathways to life and death显示文摘 | King K L Cidlowski J A | 1995 | Cell Biochem1995，58，2： | 1 |
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